Why are the symptoms of the prolonged COVID reduced up to 80% in the vaccinated

Among the most common symptoms of prolonged COVID-19 are fatigue, difficulty breathing and mental fog (Getty Images)
Among the most common symptoms of prolonged COVID-19 are fatigue, difficulty breathing and mental fog (Getty Images)

The Prolonged COVID or post-COVID-19 syndrome is an emergent and complex health problem that is affecting humanity and will have an impact in the future, even after the coronavirus pandemic. Among the most common symptoms se encuentra la fatigue, la difficulty para respira y la cognitive disfunción, pero también otros que afectan a los sistemas musculoesquelético, cardiac y central nervosa y que, por lo general, repercuten en el funcción cotidiano de las personas afectadas.

Un estudio realizado en Israel aportó más pruebas sobre los beneficios de aplicarse las vacunas contra el COVID-19 como una manera de reducir el riesgo y el impacto del COVID Prolongado.

Ya se sabía que los symptoms del Covid Prolongado pueden fluctuar o recaer con el tiempo. The most prevalent are fatigue (approximately 58%), lack of air (24%), joint pain (19%), chest pain (16%)2,3, head pain (44%), palpitations (11%), physical limitations, depression (12%) and insomnia (11%). These symptoms pueden surgir después de la recuperación inicial de un episodio agudo de COVID-19 o ser symptoms persistent que no se resuelven después de la infection.

Michael Edelstein led a study in Israel on the impact of vaccination on the risk of developing COVID Prolonged/Archive
Michael Edelstein led a study in Israel on the impact of vaccination on the risk of developing COVID Prolonged/Archive

The new study was carried out by researchers at the Azrieli Faculty of Medicine at the Bar-Ilan University in Israel. They demonstrated that the vaccination with at least two doses of the vaccines developed by the companies Pfizer and BioNTech drastically reduces the majority of long-term symptoms that individuals declare months after contracting the infection with the coronavirus.

In the investigation, eight of the ten most common symptoms were registered between 50 and 80% less among individuals who received at least two doses of the COVID-19 vaccine en comprásiona con los que no gívenor ninguna dosis.

The study was published in the magazine npj Vaccinesdel grupo editorial que publica Nature. It was directed by professor Michael Edelstein, of the University of Bar-Ilan, in collaboration with the teams of infectious diseases and informatics of three of the hospitals affiliated to the Faculty in the north of Israel: Centro Médico Baruch Padeh, Centro Médico Ziv y Galilea Medical Center. Paul Otiku, doctoral student of Facultad Azrieli de Bar-Ilan, performed the major part of the statistical analysis.

Eight of the ten most common symptoms of the Prolonged COVID-19 were registered between 50 and 80% less among those who received at least two doses of the vaccine compared to those who did not receive a dose/Archivo
Eight of the ten most common symptoms of the Prolonged COVID-19 were registered between 50 and 80% less among those who received at least two doses of the vaccine compared to those who did not receive a dose/Archivo

Almost 3,500 adults in Israel participated in the study, que fue realizado between July and November 2021. These people completed a survey available in four commonly spoken local languages ​​-Hebrew, Arabic, Russian and English- with a variety of questions about the previous infection of COVID-19, the state of vaccination and cualquier síntoma que estuvieren experimentando.

More than half of the participants (2,447) declared no previous infection with the coronavirus, while 951 were infected. Among those who had the infection, 637 (67%) received at least two doses of vaccine. Of the 2,447 individuals who did not declare any previous infection, 21 (0.9%) received one dose, 1,195 (48.8%) received two doses, 744 (30.4%) received three doses and the rest were not vaccinated ( 19.9%).

Los researchers compararon a los individuos vacunados con los non vacunados en cuanto a los symptoms post-agudos que declararon. After adjusting factors such as age and the time elapsed from the infection to the response to the survey, descubrieron que la vaccination con dos o más dosis de la vaccine de la vacuna de ARN mensajero se asociaba a un menor riesgo de notificar los symptoms of COVID Prolongado más comunes.

It was discovered that vaccination with two or more doses of messenger RNA vaccine was associated with a lower risk of prolonged COVID symptoms (Getty)
It was discovered that vaccination with two or more doses of messenger RNA vaccine was associated with a lower risk of prolonged COVID symptoms (Getty)

Between the population of the actual study, the most commonly reported symptoms -fatigue, dolor de cabeza, debilidad de las extremitas y persistent muscular dolor- se redujeron en un 62%, 50%, 62% y 66%, respectively. La falta de aire se redujo en un 80% y el dolor persistente muscular en un 70%.

The study, which received funding from the Harvey Goodstein Foundation, contributed to the lack of information in the world about the impact of vaccination on the prolonged COVID. “We don’t understand everything that is happening in the months and years following COVID-19 in terms of health and physical and mental health,” said Professor Edelstein.

“Como el COVID Prolongado parece afectar a tanta gente, era importante para nosotros comprador si las vacunas podian ayudar a aliviar los symptoms. Every time it is more clear that the vaccines protect not only against the disease but, as they suggest the results of this study, against the long-term effects of the COVID-19, que a veces cambian la vida”, resaltó el experto.

His study was the first of a current project put into action to monitor a large cohort of individuals from all sectors of Israel with the aim of understanding the impact of vaccines on the quality of life in the long term, the different variants del coronavirus y los symptoms del COVID Prolongado.

En Israel is carrying out a follow-up of people to understand the impact of vaccines on long-term quality of life and the symptoms of COVID Extended/Archive
En Israel is carrying out a follow-up of people to understand the impact of vaccines on long-term quality of life and the symptoms of COVID Extended/Archive

They also recently found out the results of another study in Italy. Sugirió que tres dosis de vacunas contra COVID-19 se asociación significante con un menor riesgo de desarrollar el COVID Prolongado entre los pacientes no hospitalizados.

El equipo italiano se propuso examiner el impacto de una triple dosis de vacunación en el desarrollo de covirus largos. Para eso, recurrieron a profesionales sanitarios que habian recibo tres dosis de la vaccine de la ARN mensajero y que no habian necesitado ser hospitalizados en caso de desarrollar una infection de larga duración. They included a total of 739 individuals with an average age of 42.8 years (25.4% men), of which 31% developed Prolonged COVID and 16% of these individuals had received three doses of the vaccine.

The dose number of the vaccine is also associated with it prolonged development of COVID, que osciló entre el 41.8% entre los individuos no vacunados, el 30% en los que tenien una sola dosis, el 17.4% después de dos dosis y el 16% en los que tenien una dosis triple de la vacuna. El trabajo se publicó en la revista JAMA.

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